Fig. 2. SF1126 induces apoptosis activation in human CRC cells. HT-29 cells (A-C), primary human colon cancer cells ("pri-Can-1/2", D and E), or primary human colon epithelial cells ("pri-Epi-1/-2", D and E) were treated with applied concentrations of SF1126. Cells were further cultured for indicated times, and caspase activation and the induction of apoptosis were tested by the assays described in the text (A-E).*p< 0.05 vs. the "C" group. The experiments were repeated three times, with similar results obtained.